TRANSFORM CHRONIC DISEASE CONTROL WITH MEDSENGINE.

Utilize guidelines and patient data to optimize medication decisions.

MedsEngine retrieves 160 patient variables and applies 855 pages of AHA / ACC / ADA guidelines to help physicians and advanced practice providers (APPs) make evidence-based medication recommendations in under 10 seconds, empowering them to markedly improve control of hypertension, type 2 diabetes, dyslipidemia, and HFrEF.

Personalized Recommendations in <10 Seconds

✓
Evidence-based
✓
Patient-specific
✓
Fits your workflow
Guideline-Directed Care
Minimize variability
Improve outcomes and quality metrics
Increase financial performance
EVIDENCE-BASED
EHR-INTEGRATED
PROVEN RESULTS
HEALTHIER PATIENTS
FINANCIAL BENEFITS
EXPLORE CHRONIC DISEASE SOLUTIONS.

EHR-integrated, guideline-directed, and evidence-based decision support - go live in as little as 2 hours.

Explore how MedsEngine supports guideline-directed and evidence-based recommedations care for each condition, integrated into your EHR.

INCREASE REVENUE. IMPROVE VALUE.

Multiple paths to improve economics with MedsEngine.

MedsEngine creates financial value through fee-for-service reimbursement, quality incentives, value-based contracts, and avoided medical costs—while also supporting programs such as CMS ACCESS and the Rural Health Transformation Program.

Chronic disease control increases financial performance.

Higher quality, fewer complications, and more efficient care help drive sustainable value.

1

Fee-for-Service Revenue

Supports increased use of Cardiovascular Risk Reduction Counseling (G0446).

$31,000
annual revenue opportunity
per clinician
Example: 1,000 eligible patients/year at $31 per patient
High value CV risk counseling
Increase physician and APP income
Easily satisfies documentation requirements
Calculate G0446 ROI →
2

Quality Ratings & Incentives

Improved performance on 8 key HEDIS/Star measures.

8 HEDIS / STAR MEASURES WE SUPPORT
5 of 8 are weighted 3X.
Controlling High Blood Pressure (CBP)
3X
Statin Therapy for Patients with Cardiovascular Disease (SPC)
1X
Glycemic Status Assessment (GSD)
3X
Kidney Health Evaluation for Patients with Diabetes (KED)
1X
Medication Adherence for Hypertension
3X
Medication Adherence for Diabetes
3X
Medication Adherence for Cholesterol
3X
Statin Use in Persons with Diabetes (SUPD)
1X
3

Value-Based Contracts

Better chronic disease control supports shared savings and risk arrangements.

Improved control rates
Supports shared savings models
Lower total cost of care
Reduced hospitalizations and ED visits
Stronger performance in meeting
payer quality targets
4

Reduced
Medical Spend

High chronic disease control rates reduce costly cardiovascular events.

ESTIMATED COSTS PER EVENT
Myocardial Infarction
$29,500
Stroke
$20-43,000
Heart Failure (admission)
$17,000
Coronary Artery Disease
$32,500
Annual savings per controlled patient
$2,500
Hypertension
$2,000
Diabetes
$780
Cholesterol
Sources: Lancet 2016; Ochsner Validation Institute 2023; J Gen Intern Med 2025; Prog Cardiovasc Dis 2022.
PROGRAM OPPORTUNITIES.

MedsEngine supports key CMS and rural health initiatives.

Support chronic disease control, quality performance, and value-based care programs.

CMS ACCESS Model

Supports organizations participating in the CMS ACCESS Model with chronic disease control, quality performance, and value-based care.

Chronic disease control (HTN, Diabetes, Cholesterol, HFrEF)
Improved quality measure performance
Supports risk and outcomes-oriented care
Aligned with CMS goals for primary care transformation

Rural Health Transformation Program

Helps rural health organizations improve chronic disease management with a low implementation burden.

Chronic disease control in rural settings
Low implementation burden
Extends guideline-directed care without requiring additional FTEs
Supports sustainability and improved health outcomes
PROVEN RESULTS. REAL-WORLD EVIDENCE.

Clinical results backed by peer-reviewed evidence.

MedsEngine delivers measurable results in real-world primary care, supported by peer-reviewed research and independent analysis.

“MedsEngine is among the most clinically rigorous and outcomes validated decision support platforms HITLAB has evaluated.In a landscape crowded with digital health promises, MedsEngine delivers something rare: a decade of real-world evidence that durably moves the needle on chronic disease control at scale.”
Stan Kachnowski, PhD, MPH
Chair, HITLAB
MEDSENGINE HYPERTENSION OUTCOMES
92%

Nation Leading Blood Pressure Control

U.S. average
48%
<140/90 goal
Achieved in <2 office visits
Sustained for 10 years
14,058
Patients
in the published study (two groups)
‍
88%
Sustained BP control
>53,000 follow-up office visits over 7 years
91%
BP Control
at Premier/AHN by the fourth follow-up visit
‍
PEER-REVIEWED PUBLICATION

The American Journal of Medicine

MedsEngine Hypertension Outcomes

Real-world evidence showing high blood pressure control with MedsEngine in primary care.

Published July 2026. Includes data from 14,058 patients with 10 years of real-world data.
Read the AJM Article →
INDEPENDENT ANALYSIS

Boost Revenue and Quality with MedsEngine — HITLAB Evidence Paper

✓
Supports G0446 reimbursement
✓
Projected $31,000 annual revenue per physician/APP
✓
Supports improved HEDIS and Star performance
✓
Independent evidence review
Read the HITLAB Evidence Paper →
FAST. SIMPLE. MINIMAL EFFORT.

Get up and running with MedsEngine in as little as 2 hours.

(About 2 hours of customer time over 2 weeks)

MedsEngine is designed for fast and minimal-effort implementation. Our detailed step-by-step implementation plans streamline setup across leading EHR platforms including athenahealth, Epic, TouchWorks EHR (Altera), and others.

Start with a No-Cost Pilot →
RAPID MEDSENGINE IMPLEMENTATION
Minimal customer effort required
Cholesterol & Diabetes
~2 hours
customer time over 2 weeks
Hypertension & HFrEF
~4 hours
customer time over 2 weeks

MedsEngine is integrated across leading EHR platforms

athenahealth
Epic
TouchWorks EHR (Altera)
eClinicalWorks
NextGen Healthcare
Azalea Health
Oracle Health (formerly Cerner)
Additional FHIR integrations available
Typical customer implementation time:
~8 hours — Cholesterol + Diabetes
~6 hours — Hypertension + HFrEF
customer time over 2-4 weeks
NO-COST PILOT

Start with a No-Cost MedsEngine Pilot

Tell us a little about your organization and EHR. We’ll follow up to discuss the best way to launch a MedsEngine pilot.

Thank you! Your submission has been received!
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Transforming
Chronic Disease Control

MedsEngine revolutionizes chronic disease control for physicians and clinicians by integrating real-time, evidence-based insights that streamline care, achieve nation-leading control rates, enhance medication adherence, and reduce healthcare costs.
‍

New Peer-Reviewed Publication

Published in The American Journal of Medicine

92% BP control achieved at the second follow-up visit in PriMED, with strong control rates sustained thereafter — published evidence supporting hemodynamic-guided hypertension treatment in primary care.

Read the Publication →
👥 14,058 Patients
♥ 92% BP Control
🏥 Primary Care
American Journal of Medicine Hypertension Hemodynamic-Guided Therapy
PriMED: 92% at second follow-up visit; Premier: 91% by the fourth visit.
The American
Journal of
Medicine
The Green Journal
Published Results
92%
BP Control
✓
$
$
Increased Revenue. Broader Value.

Explore the Financial Impact of MedsEngine

Estimate immediate fee-for-service revenue, while MedsEngine’s clinical modules support larger long-term value.

Immediate Revenue Long-Term Value Better Outcomes Lower Costs Shared Savings Value-Based Payments
Click to Expand
Calculate Fee-for-Service ROI
Takes about 60 seconds
ROI Calculator

Estimate Immediate Fee-for-Service Revenue

Enter a few practice assumptions to estimate fee-for-service revenue, associated costs, and net return over three years.

This calculator estimates fee-for-service income only.

MedsEngine can also create substantially greater long-term value through improved HEDIS and UDS performance, stronger Star Ratings, shared savings, value-based payments, better chronic disease control, and fewer costly complications.

Practice Inputs

$25–$31 depending on geography and payer.
Static MedsEngine cost assumption: $0.45 per participating patient per month ($5.40 annually per counseling opportunity).

Estimated Results

3-Year Cumulative Net Revenue
$0
Net revenue after estimated MedsEngine cost.
Patients / Month
0
Estimated new patients counseled each month.
ROI on Cost
0.0x
Net revenue divided by MedsEngine cost.
Year 1 Population Reached
0%
0 of 0 patients
Year 2 Population Reached
0%
0 of 0 patients
Year 3 Population Reached
0%
0 of 0 patients
Year Billable Events Cumulative Patients Reached % of Population Reached Income Cost Net Revenue
Year 1 0 0 0% $0 $0 $0
Year 2 0 0 0% $0 $0 $0
Year 3 0 0 0% $0 $0 $0

This calculator is an estimate only. It assumes each patient can generate counseling income once per year, and that MedsEngine cost is matched to each annual counseling event. Population reached is shown as the cumulative percentage of the total adult patient population counseled by the end of each year.

📈
EVIDENCE
REPORT
20–30x Validated ROI
Independent HITLAB Evidence

HITLAB Publishes Independent Evidence Report on MedsEngine

Independent analysis validates MedsEngine’s ability to improve chronic disease outcomes while creating significant financial value for health systems, payers, employer clinics, and primary care organizations.

The report highlights >92% blood pressure control sustained for 10 years across 14,000+ patients and a validated 20–30x ROI.

✓
Reduce avoidable events, improve quality measures (HEDIS, Star Ratings, UDS), and support new or underutilized revenue opportunities.

Ideal for CMS ACCESS & Rural Health Transformation Programs

MedsEngine helps physicians and clinicians rapidly achieve control of chronic disease outcomes while generating measurable ROI under CMS ACCESS and Rural Health Transformation programs.

CMS ACCESS

Rapidly achieve control. Earn performance payments.

  • Supports CMS ACCESS Track 1 (eCKM) and Track 2 (CKM) clinical pathways
  • Hypertension: BP control rates >90% (22 mmHg systolic reduction); sustained for 10 years
  • Cholesterol: population control per AHA/ACC guidelines
  • Diabetes: A1c reduction to personalized A1c goal
Rural Health Transformation Program

Control 4 chronic diseases in rural settings.

  • Rapid evidence-based medication recommendations at the point of care
  • Achieves efficiency, sustainability, and scalability
  • Increases APP skillset and confidence
  • Built by physicians for clinicians to improve office workflow
  • Innovative technology improves patient outcomes and reduces cost
How to Succeed in Rural Health Transformation
A medical professional reading a patients blood pressure with a blood pressure cuff

A New Era of control in hypertension, type 2 diabetes, cholesterol, and heart failure is here.

MedsEngine is a clinical decision support software solution that delivers real-time, personalized medication recommendations. 

It uses state-of-the-art cloud technology and integrates with electronic health record systems that support industry-standard Fast Healthcare Interoperability Resources (FHIR). MedsEngine codifies expansive clinical guidelines and uses EHR data to recommend evidence-based and guideline-directed medical therapy without affecting patient throughput. With MedsEngine, patients receive consistent, personalized care from both physicians and advanced practice providers.

Our Solutions

Worldwide chronic disease control is disturbingly inadequate.

Despite the trillions invested in chronic care management, fewer than half of all patients achieve their treatment goals, highlighting a deep need for more effective strategies. MedsEngine partners with physicians and clinicians as a powerful ally in the quest for improved chronic disease control.
A medical professional looking at a computer while taking notes

We're committed to equipping physicians and clinicians with the tools they need to transform the future of chronic disease control.

Seamless integration using Smart on FHIR allows physicians and clinicians to navigate MedsEngine recommendations from their EHR system.
Our patient-centric approach actively involves patients in understanding their condition and treatment, bolstering medication adherence and helping to improve outcomes.
About Us

Together, we can achieve clinical excellence.

Physicians and clinicians partnering with MedsEngine are experiencing transformative impacts in chronic disease control.

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Setting new benchmarks for hypertension control 

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Achieving higher HEDIS scores

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Lowering medical costs

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Supporting
high-quality care across physicians and clinicians

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Improving patient satisfaction

Bring personalized, evidence-based medication recommendations into your existing EHR workflow.